What is an anticholinergic effect that may result from the use of MAOIs?

Xerostomia, or dry mouth, is an anticholinergic effect that can occur from the use of monoamine oxidase inhibitors (MAOIs). MAOIs can influence neurotransmitter systems that regulate salivary flow. When these pathways are affected, one common outcome is a reduction in saliva production, leading to the sensation of dryness in the mouth. This effect is particularly relevant because it reflects the potential side effects associated with medications that alter neurotransmitter balance. Understanding this relationship helps in managing patient expectations and addressing concerns that may arise during treatment with MAOIs.