Which benzodiazepine is known for its rapid onset and short duration of action?

Halcion, or triazolam, is recognized for its rapid onset of action and relatively short half-life compared to other benzodiazepines. This makes it particularly useful in treating insomnia, as it helps patients fall asleep quickly without lingering effects the next day. It acts on the central nervous system by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA), leading to sedative effects.

The rapid onset is usually within 15–30 minutes after administration, which is ideal for patients who need to manage acute sleep onset issues. The shorter duration of action, typically around 3 to 6 hours, helps minimize daytime sedation, making it less likely to impair daily activities after a night’s sleep.

While the other options, such as Xanax and Ativan, may also have rapid effects, they are generally longer acting than Halcion. Temazepam has a longer duration of action and is used more for sleep maintenance rather than immediate onset. Thus, Halcion stands out as the benzodiazepine with both a quick effect and brief duration, making it particularly effective for certain clinical scenarios.